"send" not working

11:04:31 AM claytonrogers@charter.net [SMTP] MailClient.Accounts.SocketException: Connection failed due to the following reason:
“Unable to read data from the transport connection: A connection attempt failed because the connected party did not properly respond after a period of time, or established connection failed because connected host has failed to respond…”

how do I get Send to work?

Try temporarily closing any VPN or antivirus applications.