cannot start em client

Em Client for My business email got problem, really need help, thanks. 

cannot start, with message below:

System.Data.SQLite.SQLiteException (0x80004005): unable to open database file

unable to open database file

   at System.Data.SQLite.SQLite3.Prepare(SQLiteConnection cnn, String strSql, SQLiteStatement previous, UInt32 timeoutMS, String& strRemain)

   at System.Data.SQLite.SQLiteCommand.BuildNextCommand()

   at System.Data.SQLite.SQLiteCommand.GetStatement(Int32 index)

   at System.Data.SQLite.SQLiteDataReader.NextResult()

   at System.Data.SQLite.SQLiteDataReader…ctor(SQLiteCommand cmd, CommandBehavior behave)

   at System.Data.SQLite.SQLiteCommand.ExecuteReader(CommandBehavior behavior)

   at System.Data.SQLite.SQLiteCommand.ExecuteNonQuery()

   at System.Data.SQLite.SQLiteConnection.Open()

   at MailClient.Storage.Data.DataStore.GetConnection(String relativeName)

   at DbRepair.CorruptionChecker.CheckCorruption()

   at DbRepair.FormCheck.Check(Object state)