Problem with S/MIME certificate

I installed a S/MIME certifcate and it is visible under “certificates and keys”. But when I want to send a Mail, eM client complains “The certificate or key you previously used to sign messages sent from … is not available. Make sure it is available or choose a different one.”

I tried this 2 2 different certificates. And they both have the same problem. Do somebody know a solution to fix this?

Thank you in advance!