Copy/pasting the text below as I found it (haven’t tested this yet):
I remember there being talk about how to get eM client to run on linux in the past and i just tried and it worked flawlessly (I think, I didn’t really like it so haven’t used it much and went back to thunderbird) using bottles with their “caffe-9.7” runner. just give it the .msi eM client installer from their website and go through the setup as normally
just for posterity: there’s this error at the start of the installation
no idea what it means so just hit okay and continue on with the installation and it will still work
and this is the runner you want:

