Em client doesn't iniciate

Every time that i try to initiate Em cliente the following message/error appears:

System.Data.SQLite.SQLiteException (0x80004005): disk I/O errordisk I/O error
   at System.Data.SQLite.SQLite3.Prepare(SQLiteConnection cnn, String strSql, SQLiteStatement previous, UInt32 timeoutMS, String& strRemain)
   at System.Data.SQLite.SQLiteCommand.BuildNextCommand()
   at System.Data.SQLite.SQLiteCommand.GetStatement(Int32 index)
   at System.Data.SQLite.SQLiteDataReader.NextResult()
   at System.Data.SQLite.SQLiteDataReader…ctor(SQLiteCommand cmd, CommandBehavior behave)
   at System.Data.SQLite.SQLiteCommand.ExecuteReader(CommandBehavior behavior)
   at System.Data.SQLite.SQLiteCommand.ExecuteNonQuery()
   at System.Data.SQLite.SQLiteConnection.Open()
   at MailClient.Storage.Data.DataStore.GetConnection(String relativeName)
   at DbRepair.CorruptionChecker.CheckCorruption()
   at DbRepair.FormCheck.Check(Object state)

Regards,
André